Co-twin control studies: vitamin C and the common cold.

نویسندگان

  • N G Martin
  • A B Carr
  • J G Oakeshott
  • P Clark
چکیده

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منابع مشابه

A co-twin control study of the effects of vitamin C.

In recent years, a number of benefits of prophylactic pharmacologic doses of vitamin C have been suggested. In addition to claims by Linus Pauling [1971] and others of a reduction in the morbidity due to the common cold and upper respiratory infections, other authors have subsequently suggested that serum cholesterol levels may be lowered [Spittle, 1971]. Some investigations have suggested that...

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Vitamin C and the common cold: using identical twins as controls.

We analysed self-reported cold data for 95 pairs of identical twins who took part in a double-blind trial of vitamin C tablets. One member of each twin pair took vitamin C and the other took a well matched placebo each day for 100 days. Vitamin C had no significant effect except for shortening the average duration of cold episodes by 19%.

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Vitamin C and the common cold: a second MZ Cotwin control study.

Self-reported cold data have been analyzed for 95 pairs of identical twins aged 14-64 who took part in a double-blind trial of vitamin C tablets. One member of each twin pair took a tablet containing 1 g vitamin C and the other took a well-matched placebo each day for 100 days. In the total sample there was no effect of vitamin C in preventing colds. However, subdivision of the data showed a si...

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Therapeutic effect of vitamin C. A co-twin control study.

Three different dosages of vitamin C, dependent on body weight, were administered to 44 school-aged monozygotic twins for five months using a double-blind, co-twin control study design. The mothers recorded daily observations of cold symptoms, and multiple biochemical, anthropometric, and psychological measurements were made at the beginning and end of the study. Paired comparisons showed no si...

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Review Article

In 1975 Thomas Chalmers analyzed the possible effect of vitamin C on the common cold by calculating the average difference in the duration of cold episodes in vitamin C and control groups in seven placebo-controlled studies. He found that episodes were 0.11 ± 0.24 (SE) days shorter in the vitamin C groups and concluded that there was no valid evidence to indicate that vitamin C is beneficial in...

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عنوان ژورنال:
  • Progress in clinical and biological research

دوره 103 Pt A  شماره 

صفحات  -

تاریخ انتشار 1982